Utilizing Magnetic Resonance Imaging
Current research focuses on utilizing magnetic resonance imaging (MRI) and functional MRI technologies to study aging and degenerative disease in awake non-human primate model. Brain activation induced by pharmacological stimulation is mapped by using endogenous blood oxygenation level dependent (BOLD) mechanism to study functional architecture of basal ganglia circuits. The study will let us better understand the anatomy, physiology and pharmacology of those structures. Another research interest is using the non-human primate parkinsonian model to investigate the basal ganglia pathways which involve Levo-dopa induced side effects. This study can lead us to find a better strategy to treat Parkinson's disease.
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